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Nat Med (2003) 9(9):11739
Check your urine midafternoon and after exercise and adjust fluid intake if the color darkens or output drops
This pharmacokinetic reality drives the gradual dose escalation protocol and explains why rushing the process typically backfires
Typical dosing of 325650 mg every 46 hours, up to 3000 mg daily, provides effective pain relief for headaches, muscle aches, and minor inflammatory conditions
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